Pathology of Muscle Notes
نویسنده
چکیده
Skeletal muscle is composed of elongated myofiber cells 1-40 mm long by 10-100 μm in diameter. Cells are multinucleated (100-300 nuclei/cell), non-branched with a parallel arrangement, and separated from each other by thin connective tissue (endomysium, perimysium, epimysium). The sarcolemmal membrane is formed by the endomysium and the basal lamina. The sarcoplasm of the myofibers has many myofibrils (80% of volume) arranged in sequence which gives muscle a distinct striation pattern (I/isotropic and A/anisotropic bands). "A" bands are larger and darker while "I" bands are lighter and shorter but contain a thin dark "Z" band in the middle. The sarcomere is the structural/functional unit of the muscle ("Z" to "Z" lines).
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تاریخ انتشار 2008